Zbigniew Gugala, MD, PhD

Associate Professor
Clinical Research


1987-1993 The Jagiellonian University, Krakow, Poland, Medical Doctor (MD)
1991-1993 The Jagiellonian University, Krakow, Poland, Faculty of Philosophy
2003 The University of Groningen, The Netherlands, Doctor of Philosophy (PhD)

Professional and Teaching Experience

1991-1993 The University of Mining and Metallurgy, Krakow, Poland, Faculty of Materials Science and Ceramics
1990, 1992, 1994-1997 AO Research Institute, Davos, Switzerland
1998-2003 Postdoctoral Research Associate, Department of Orthopaedic Surgery, Baylor College of Medicine, Houston, TX

Selected Publications
  1. Gugala Z, Gogolewski S. Regeneration of Segmental Diaphyseal Defects in Sheep Tibiae using Resorbable Polymeric Membranes: A preliminary study. J Orthop Trauma 13(3):187-195, 1999.
  2. Gugala Z., Gogolewski S. In Vitro Growth and Activity of Primary Chondrocytes on a Resorbable Polylactide Three-Dimensional Scaffold. J Biomed Mater Res 49(2):183-191, 2000.
  3. Cobos J, Lindsey RW, Gugala Z. The Cylindrical Titanium Mesh Cage for the Treatment of a Long Bone Defect: Description of a New Technique and Report of Two Cases. J Orthop Trauma 14(1):54-59, 2000.
  4. Nana A, Gugala Z, Lindsey RW, Caram P, Dickson JH. Bending of the Cotrel-Dubousset Instrumentation after Direct Trauma. A Case Report. Spine 25(7):891-894, 2000.
  5. Gugala Z, Nana A, Lindsey RW. Tibial Intramedullary Nail Distal Interlocking Screw Placement: A Comparison of the Free-Hand versus Distally-Based Targeting Device. Injury 32 (Suppl 4):21-5, 2001.
  6. Olmsted EA, Blum JS, Rill D, Yotnda P, Gugala Z, Lindsey RW, Davis AR. Identification of a Novel Regulatory Mechanism for AdBMP2 Expression in Human Bone Marrow Stromal Cells. J Cell Biochem 82(1):11-21, 2001.
  7. Olmsted EA, Gugala Z, Gannon FH, Yotnda P, McAlhany R, Lindsey RW, Davis AR. Use of Chimeric Adenovirus Vector Enhances BMP-2 Production and Bone Formation. Hum Gene Ther 13(10):1337-1347, 2002.
  8. Davis AR, Olmsted-Davis E, Gugala Z, Moran K, Lindsey RW, Shore, Kaplan F, Gannon FH. Mechanisms of BMP2-Induced Heterotopic Bone Formation. J Bone Miner Res 17:S302 (Suppl 1), 2002.
  9. Gugala Z, Gogolewski S. Healing of Critical-Size Segmental Bone Defects in the Sheep Tibiae using Bioresorbable Polylactide Membranes. Injury 33 (Suppl 2):B71-76, 2002.
  10. Gugala Z, Lindsey RW. Classification of Gunshot Injuries in Civilians. Clin Orthop 408:65-81, 2003.
  11. Lavoie S, Lindsey RW, Gugala Z, Kirking B, Hipp JA. Threaded Interbody Cages for the Lumbar Fusion: An in vitro Study of Load Sharing and Kinematics. Clin Orthop 408:174-179, 2003.
  12. Gugala Z, Olmsted-Davis EA, Gannon FH, Lindsey RW, Davis AR. Osteoinduction by Ex Vivo Adenovirus-Mediated BMP2 Delivery Is Independent of Cell Type. Gene Therapy 10(16):1289-1296, 2003.
  13. Lindsey RW, Gugala Z. Clearance of Cervical Spine in the Obtunded Patient. SpineLine: Curve/Countercurve 4:20-26, 2003.
  14. Olmsted-Davis EA, Gugala Z, Gannon FH, Lindsey RW, Davis AR. Primitive Hematopoetic SP Cells Are Precursors of the Osteoblasts. Proc Natl Acad Sci USA 100(26):15877-15882, 2003.
  15. Davis E, Gugala Z, Camargo F, Gannon FH, Jackson KJ, Kinestra KA, Shine HD, Lindsey RW, Hirsche KK, Goodell MA, Brenner MK, Davis AR. A Common Stem Cell for Blood and Bone. J Bone Miner Res 18:S344 (Suppl 2), 2003.
  16. Gugala Z, Gogolewski S. Differentiation, Growth, and Activity of Rat Bone Marrow Stromal Cells on Polylactide Membranes with Well-Defined Surface Characteristics. Biomaterials 25:2299-2307, 2004.
  17. Gugala Z, Gogolewski S. Protein Adsorption, Attachment, Growth, and Activity of Primary Osteoblasts on Polylactide Membranes. Biomaterials 25:2341-2351, 2004.
  18. Lindsey RW, Gugala Z. Cylindrical Titanium Mesh Cylindrical Cage for the Reconstruction of Long Bone Defects. Osteo Trauma Care 12:108-115, 2004.
  19. Lindsey RW, Gugala Z. Nonunion of the Distal Tibia Treated by Reamed Intramedullary Nailing. J Orthop Trauma 19(2):145, 2005.
  20. Gugala Z, Gogolewski S. The In Vitro Growth and Activity of Sheep Osteoblasts on Three-Dimensional Scaffolds from Poly(L/DL-lactide) 80/20%. J Biomed Mater Res 25(12):2341-2351, 2005.
  21. Gugala Z, Gogolewski S. The in vitro growth and activity of sheep osteoblasts on three-dimensional scaffolds from poly(L/DL-lactide) 80/20%. J Biomed Mater Res A 75(3):702-709, 2005.
  22. Fouletier-Dilling CM, Bosch P, Davis AR, Shafer JA, Stice SL, Gugala Z, Gannon FH, Olmsted-Davis EA. Novel compound enables high-level adenovirus transduction in the absence of an adenovirus-specific receptor. Hum Gene Ther 16(11):1287-1297, 2005.
  23. Gugala Z, Gogolewski S. Attachment, growth, and activity of rat osteoblasts on polylactide membranes treated with various low-temperature radiofrequency plasmas. J Biomed Mater Res A 76(2):288-299, 2006.
  24. Torga-Spak R, Gugala Z, Lindsey RW. Case reports: A subtrochanteric femur fracture with long intramedullary femorotibial nail for knee arthrodesis. Clin Orthop 444:256-60, 2006.
  25. Lindsey RW, Gugala Z, Milne E, Sun W, Gannon FH, Latta LL. The efficacy of cylindrical titanium mesh cage for the reconstruction of a critical-size canine segmental femoral diaphyseal defect. J Orthop Res 24(7):1438-1453, 2006.
  1. Gugala Z. “Resorbable Polymeric Scaffolds for Tissue Repair, Regeneration, and Engineering”. Krakow, Poland: AA Press, 2003. (ISBN 83-919149-0-7)
Book Chapters
  1. Lindsey RW, Gugala Z. Spinal Cord Injury as a Result of Ballistic Trauma. In: “Spine: State of the Art Reviews” Spinal Cord Injuries 13(3). Chapman JR (ed). Philadelphia: Hanley & Belfus, Inc., 1999, pp. 529-547. (ISBN 1-56053-291-2).
  2. Lindsey RW, Gugala Z. Subtrochanteric Fractures of the Femur. In: “Fracture: Current Diagnosis and Treatment”. Moehring HD, Greenspan A (eds). McGraw Hill, 2000, pp. 107-115. (ISBN 0-0713-5902-8).
  3. Lindsey RW, Pneumaticos SG, Gugala Z. Management Techniques for Spinal Injuries. In: “Skeletal Trauma”. Browner B, Jupiter J, Levine A, Trafton P, (eds). Elsevier Science, 2003, pp. 746-776. (ISBN 0-7216-9175-7).
  4. Lindsey RW, Gugala Z, Pneumaticos SG. Injuries of the Vertebrae and Spinal Cord. In: “Trauma” 5th Edition. Moore EE, Feliciano DV, Mattox KL (eds). McGraw Hill, 2003, pp. 459-492. (ISBN 0-07-137069-2).
  5. Lindsey RW, Gugala Z. Gunshot Injuries to the Thoracolumbar Spine. In: “The Management of Thoracolumbar Fractures” AAOS Monograph No. 26. Reitman C (ed). Rosemont, IL: The American Academy of Orthopaedic Surgeons, 2004, pp. 85-96. (ISBN 0-89203-322-3).
  6. Lindsey RW, Gugala Z. Clearing of the Cervical Spine. In: “The Cervical Spine” 4th Edition. The Cervical Spine Research Society Editorial Committee: Clark CR, Benzel EC, Currier BL, Dormans JP, Dvořák J, Eismont F, Garfin SR, Herkowitz HN, Ullrich CG, Vaccaro AR.. Philadelphia: Lippincott Williams & Wilkins, 2005, pp. 375-386. (ISBN 0-7817-3576-9).
  7. Lindsey RW, Gugala Z, Torga-Spak R. The Long-Term Retention versus Removal of Orthopaedic Trauma Fixation Implants. In: “Orthopaedic Knowledge Update: Trauma” 3rd Edition. Tornetta P, Baumgaertner M (eds). American Academy of Orthopaedic Surgeons, Rosemont 2005, pp.141-148. (ISBN 0-89203-347-9).
  8. Lindsey RW, Gugala Z. Management of Open Fractures. In: “Techniques in Fracture Surgery”. Tornetta P III (ed). Mosby/Saunders. In Press.
  9. Lindsey RW, Gugala Z. Pre-Imaging Cervical Spine Clearance Guidelines in Trauma Patients. In:“The Cervical Spine”. Vaccaro AR (ed). Lippincott Williams & Wilkins, Philiadelphia. In Press.
  10. Lindsey RW, Gugala Z, Pneumaticos SG. Injuries of the Vertebrae and Spinal Cord. In: “Trauma” 6th Edition. Moore EE, Feliciano DV, Mattox KL (eds). In Press.