MedPage Today (Internet) 06/21/06 Whether a man with prostate cancer is treated with androgen deprivation may depend more on his choice of urologist than on the nature of his tumor or his age, researchers here suggested. "The use of androgen deprivation therapy for prostate cancer has been increasing, even in settings for which there is weak or no evidence of efficacy," wrote Vahakn B. Shahinian, M.D., M.S., and colleagues, of the University of Texas Medical Branch here, in the June 21 issue of Journal of the National Cancer Institute. The reason this is important, they said, is that although androgen deprivation combined with radiation therapy has been shown to improve survival in men with locally advanced prostate cancer, the therapy is associated with significant side effects, including sexual dysfunction, osteoporosis, and fractures.