Boston Globe (Internet / Print) 05/22/06 http://www.boston.com/news/globe/health_science/articles/2006/05/22/how_the_nose_knows/ Two years ago, Linda Buck and an early colleague, Richard Axel, shared the Nobel Prize for their work chipping away at unraveling the mystery of how the brain translates odor chemicals inhaled in the nose. This spring, Buck published a study in Science showing how the brain, once it receives a coded message for a particular smell, begins to ''decode" that message. In her recent Science study, Linda Buck and former fellow Zhihua Zou, now a neuroscientist at the University of Texas Medical Branch in Galveston, reported that there are neurons in a part of the brain called the olfactory cortex that seem to read the receptors' code -- they fire only when stimulated by two or more neurons that connect all the way back to the original odor receptors in the nose. These neurons are linked to various parts of the brain, and Zou and Buck are still trying to figure what that means.