In this week’s column, UTMB’s Dr. Victor S. Sierpina writes that heart disease symptoms in women are often subtle and less obvious than in men. The common triad of chest pain brought on by exercise and relieved by rest, which is a common, presenting sign of heart problems is not always so clear-cut in women. Because women’s heart disease tends to occur in smaller vessels and is more diffuse symptoms can present more generically. These include fatigue, shortness of breath, indigestion, nausea, faintness, upper back, neck or shoulder pain.